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fast growing

skylar kraft

on 13 May 2010

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Transcript of Cancer

Wilms Cancer def. Wilms' tumor is a rare malignant kidney cancer, also known as nephroblastoma, most commonly found in children from ages 3 to 4. Wilm's tumor can go undetected for a while with out feeling any pain, you may appear to be healthy with this cancer. It is usually found before it spreads to the rest of the body. These are some symptoms to look for when you are diagnosed with Wilm's cancer.

Abdominal swelling
An abdominal mass you can feel
Blood in the urine
Reduced appetite
High blood pressure
Stomach pain
Nausea Epidemiology It is uncommon for Wilms' tumor to run in families. Less than 2 percent of cases will have an affected relative. Most cases of Wilms' are considered sporadic (occur by chance) and are the result of genetic mutations that affect cell growth in the kidney. These mutations generally arise after birth, but, in some cases, children are born with a genetic alteration that predisposes them to cancer.

It is the most common type of renal (kidney) cancer and accounts for about 6 percent of all childhood cancers. Approximately 400 children in the United States are diagnosed with a Wilms' tumor each year. The disease can occur at any age between infancy and 15 years, but, in most cases, the tumor is detected by the age of 3. This cancer affects males and females equally.
the German surgeon (1867–1918) who first described this kind of tumor.
It is listed as a rare diseased by the Office of Rare Diseases of the National Institute of Health because it affects less than 200,000 people in the US population. Approximately 5.6 percent of the "children cancers" are Wilms’ tumors.

Historical Names Wilms disease only grows in the kidneys where it kills the white blood cells that try to fight the disease. the cancer will start on one kidney and will eventually travel to the other kidney other than that this cancer doesn't do to much moving. The spreading of the disease can take from up to 5 months to a 8 months to spread to both kidneys, with any drugs being taken. This cancer is malignant, which means it does not spread. It only spread through the organ that is diseased, it does not move from organ to organ. the progressionof this cancer can be stopped by drug these drug will attack the bad cells so that they stop growing it does not completely kill the disease but does stop the cancer from killing the whole organ. Course of disease Determining the prognosis and long-term survival of children with Wilms' tumor are as follows:

Whether anyone else in the family has it
extent of the disease
age and health
size of tumor
response to therapy
tolerance of medications, procedures, and therapy
developments in treatment

Like cancer, prognosis and long-term survival can vary for each patient. Prompt Medical attention and therapy are important for the best possible prognosis. Continued visits are essential for the child diagnosed with a Wilms' tumor. Side effects of chemotherapy and radiation can occur in the patient that survives this cancer. New methods are being discovered to improve treatment and to decrease complications.
Prognosis Treatments Surgery - to remove all of the kidney or just part of the kidney.

Biopsy - needed if the tumor is too large to be removed. A biopsy is also necessary for diagnosis.

Chemotherapy - a drug treatment that works by interfering with the cancer cell's ability to grow or reproduce. Different groups of drugs work in different ways to fight cancer cells and shrink tumors. While chemotherapy can be quite effective in treating certain cancers, there can be many adverse side effects during treatment. Chemotherapy it is introduced to the bloodstream and travels throughout the body to kill cancer cells. Chemotherapy can be given: as a pill to swallow or as an injection into the muscle or fat tissue

Radiation therapy - uses rays from a specialized machine to damage or kill cancer cells and shrink tumors.

Stem cell transplant - Stem cells develop into red blood cells to carry oxygen, white blood cells to fight disease and infection, and platelets to aid in blood clotting. Transplantation of normal stem cells from another person is used to help restore normal blood production in patients whose own ability to make any or all of these blood cells has been stopped by cancer.

Blood pressure monitoring - essential when a kidney tumor is present.

supportive care - any type of treatment to prevent and treat infections.

Impact on body sytems The kidneys are a part of the urinary system, they regulate the body's fluid volume, mineral composition and acidity by excreting and reabsorbing water. This helps balance these substances, sodium, potassium, chloride, calcium, magnesium, sulfate, phosphate and hydrogen, in the body and keep their normal concentrations in the fluid. Since the kidneys play such a big rool inthe urinary system the other parts of this system would mostly stop working also if the kidneys were infected with wilms cancer. Once the kidneys stop filtering out fluid your bladder can become intoxicated and you could possibliy pick up another disease like bladder infection.

Wilm's cancer is also called:
The childrens cancer, WT1, WARG, Nephroblastoma.
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