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Genetic Disease

Sickle cell Anemia
by

Donricko Greene

on 23 March 2011

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Transcript of Genetic Disease

Sickle Cell Anemia symptoms Enlarged Spleen
Chronic Anemia
Lethargy
Weakness
Joint Pain
Blood Clot Formation
Fever
Swelling of the hands and feet
Pain in the chest, abdomen, limbs, and joints
Nosebleeds and frequent upper respiratory infections Facts More common in Africans then any other ethnicity.
Sickle-shaped red blood cells.
Painful events are most common symptoms.
Majority of cases go uncured.
Some cases are cured via Bone Marrow transfusion.
Medications and Treatments Anti-Biotics
Pain Relievers
Hydroxyurea
Blood/Bone Marrow Transplant/Transfusion
Vaccines
Stages Retinal capillaries become plugged by sickle cells.
Peripheral Arteiovenous Anastomoses
Nevovascularization
Vitreous hemorrhage secondary to leakage from fragile Nevovascular vessels.
Tractional retinal detachment, due to vitreous hemmorhage scars, causing vision loss.
distribution / Prognosis This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
Sources http://www.cdc.gov/NCBDDD/sicklecell/data.html
Full transcript