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Transcript of Genetic Disease
Blood Clot Formation
Swelling of the hands and feet
Pain in the chest, abdomen, limbs, and joints
Nosebleeds and frequent upper respiratory infections Facts More common in Africans then any other ethnicity.
Sickle-shaped red blood cells.
Painful events are most common symptoms.
Majority of cases go uncured.
Some cases are cured via Bone Marrow transfusion.
Medications and Treatments Anti-Biotics
Blood/Bone Marrow Transplant/Transfusion
Stages Retinal capillaries become plugged by sickle cells.
Peripheral Arteiovenous Anastomoses
Vitreous hemorrhage secondary to leakage from fragile Nevovascular vessels.
Tractional retinal detachment, due to vitreous hemmorhage scars, causing vision loss.
distribution / Prognosis This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.