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Breast Cancer

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by

courtney dagostino

on 10 December 2015

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Transcript of Breast Cancer

Causes: Genetics, Environmental, etc
Exact cause is not known, but what is known is that all cancers are caused by damage to a cell's DNA.
Treatment Options and Survival Rate
Radiation treatment
Chemotherapy
Tumor excision
Clinical trials
Risk Factors
Current Research
Doctors are researching to pin-point the exact causes, such as endocrine(hormone) disruptions, environment causes, diet, and lifestyle choices to help prevent new cases of Breast Cancer
Breast Cancer & the Cell Cycle
All cancers develop when normal, healthy cells form mutations in DNA, and begin to proliferate uncontrollably.
Breast Cancer


Rate of Occurrence
Estimated risk of developing breast cancer according to age

• Risk up to age 29, 1 in 2,000.
• Risk up to age 39, 1 in 215.
• Risk up to age 49, 1 in 50.
• Risk up to age 59, 1 in 22.
• Risk up to age 69, 1 in 13.
• Lifetime risk, 1 in 8.

Statistics
In 2015, an estimated 231,840 new cases of invasive breast cancer are expected to be diagnosed in women in the U.S., along with 60,290 new cases of non-invasive breast cancer.
For women in the U.S., breast cancer death rates are higher than those for any other cancer, besides lung cancer.
About 5-10% of breast cancers can be linked to gene mutations (abnormal changes) inherited from one’s mother or father.
About 85% of breast cancers occur in women who have no family history of breast cancer.
About 1 in 8 U.S. women (about 12%) will develop invasive breast cancer over the course of her lifetime.
Who does it effect?
White women have the highest incidence of breast cancer, followed by Black, Hispanic, Asian/Pacific Islander and American Indian/Alaska Native women. The risk of developing breast cancer is higher in women who have close relatives with the disease. Having a mother, sister, or daughter, referred to as a first-degree relative, doubles a woman’s chance of developing breast cancer.
Symptoms
Men & Women

Lump on chest
Breast soreness
Skin dimpling or puckering
Swollen lymph nodes under the arm
Nipple retraction
Discharge from the nipple
By Carly Malestein,
Byron Hitchner, and
Courtney D'Agostino

DO NOT CAUSE: caffeine, deodorant, microwaves, and cellphones.
Being female. Women are more likely than men to develop breast cancer
Personal and family history. You are most likely to develop breast cancer if you had it before or someone in your family had it as well
Inherited genes. Certain gene mutations that increase the risk of breast cancer can be passed from parents to children. The most common gene mutations are referred to as BRCA1 and BRCA2.
Radiation exposure.
Obesity
Drinking alcohol
Having never been pregnant
Breast tissue is more susceptible to developing cancer. The female hormone estrogen stimulates breast cell division, which can increase the risk of breast cancer. Furthermore, breast cells are not fully mature in girls and young women who have not had their first full-term pregnancy. Breast cells which are not fully mature bind carcinogens more strongly than and are not as efficient at repairing DNA damage as mature breast cells. Therefore, it is very important to reduce exposure to cancer causing agents during the critical periods in a woman's life.
Sources
Causes of Breast Cancer :: The National Breast Cancer Foundation. (n.d.). Retrieved December 10, 2015, from http://www.nationalbreastcancer.org/causes-of-breast-cancer
Signs and symptoms of breast cancer in men. (n.d.). Retrieved December 10, 2015, from http://www.cancer.org/cancer/breastcancerinmen/detailedguide/breast-cancer-in-men-signs-symptoms
Breast Cancer Symptoms. (n.d.). Retrieved December 10, 2015, from http://www.webmd.com/breast-cancer/guide/understanding-breast-cancer-symptoms

Learn About Survival Statistics for Breast Cancer at Susan G. Komen®. (n.d.). Retrieved December 10, 2015, from http://ww5.komen.org/BreastCancer/ChancesForSurvivalBasedOnCancerStage.html

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