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Ipsilateral changes to median nerve trauma-an fMRI study

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Lotta Fornander

on 8 June 2015

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Transcript of Ipsilateral changes to median nerve trauma-an fMRI study

Ipsilateral cortical changes in response to median nerve injury

Lotta Fornander, Torbjörn Nyman, Maria Engström, Tom Brismar and Thomas Hansson
Remaining loss of sensory function
Cold intolerance

Loss of working capacity and quality of life
Young age at injury is the best predictive factor of sensory outcome


4 patients with median nerve injury at the wrist. Minimum 2 years since suture.
10 healthy volunteers
Sensory examination
Functional magnetic resonance imaging
Laterality index= (CL-IL)/(CL+IL)
Is there increased activity in the ipsilateral hemisphere in patients with median nerve trauma and repair?

Patients with median nerve injury use other areas of the brain to compensate for the changes in the contralateral primary somatosensory cortex
We found a contralateral reorganisation

a shift of activity to the ipsilateral hemisphere
Department of Orthopedic Surgery, Vrinnevi Hospital, Norrköping; Department of Plastic Surgery, Hand Surgery and Burns, Linköping University Hospital; Karolinska Institutet, Stockholm; Linköping University
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