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Alexander Fleming

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Oluoma Obi

on 24 September 2014

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Transcript of Alexander Fleming

Fleming's discovery of the lysozyme also happened to be an accident. While cleaning his cleaning out his usual clutter of test tubes he noticed a colony of a yellowish bacteria growing in one of them. Another thing he noticed was that the mucus that had fallen from his nose two weeks earlier had absolutely no bacteria.
Lysozyme could potentially kill off some bacteria without harming human cells. Because of this Fleming was keen to find out the significance of this substance and research its properties. Details were published in his article of 1922.
Alexander Fleming
Background
So he would be what one would call an all around scientist. ( All though all he did was make mistakes)(Scottish biologist, pharmacologist and botanist. He wrote many articles on bacteriology, immunology, and chemotherapy.)
He discovered the enzyme lysozyme (1921) and the antibiotic substance penicillin (1928).
He spent his teenaged years attending classes at Regent Street Polytechnic, working as a shipping clerk. Then in 1901 he won a scholarship to St. Mary’s Hospital Medical School in Paddington, London, which remained his professional home for the rest of his life.
Alexander Fleming also contributed immensely towards medical sciences with his writings on the subjects of bacteriology, immunology and chemotherapy.

Discovery of Penicillin
So basically, Alexander Fleming was a clumsy guy.
How?
He discovered everything by accident.
He was investigating a bacteria called staphylococcus
Staphylococcus: bacteria that causes boils and disastrous infections in patients with weakened immune systems.
Before he left for a two week vacation, a petri dish containing a staphylococcus culture was left on a lab bench and wasn't placed in the incubator.
Somehow a penicillium mold floated up a stairwell from the lab below where various molds were being cultured.
The temperature conditions during his vacation enabled the penicillium mold and the bacteria to grow and......
Voila! Penicillin!!!
Lysozyme
Sir Alexander Fleming and Dr. Gottlieb congratulate Prof. Callerio who first introduced the use of lysozyme in the medical practice.
Alexander Fleming receiving the
Nobel prize from King Gustaf V
of Sweden ( in 1945
The guy who discovered everything through serendipity
Serendipity - By accident
"One sometimes finds what one is not looking for
(Sir Alexander Fleming)


During World War 1, Alexander Fleming served as a captain in the Royal Medical Corps, working in the battlefield hospitals in France.
In France, Fleming had witnessed large numbers of soldiers dying from infected wounds. He realized that the antiseptics being used destroyed the patient’s immune system and didn’t effectively stop the invading bacteria. He set about trying to find anti-bacterial agents.
Alexander Fleming died in 1955. He had a heart attack.
Background Continued...
"One sometimes finds what one is not looking for"
(Sir Alexander Fleming)
Full transcript