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Transcript of phenelzine
In Weight death or
suicide Feelings of worthlessness Energy loss Symptoms Hydrazine GABA Anxiolytic
Effect Initial Dose Early phase treatment Maintenance
dose Absorption Tmax
= 43 minutes =19.8 ng/mL Its effect lasts for several weeks Metabolism 73% - 96 hours phenylacetic acid and parahydroxyphenylacetic Elimination half-life elimination
= 11.6 hrs. Treat symptoms of depression:
thoughts of death or suicide hypertension
syndrome vitamin B6 Barbiturates Clomipramine
(Anafranil) Insulin agitation confusion difficulty
headache fever &
of Mania or
Of Therapy Cmax http://www.nlm.nih.gov/medlineplus/depression.html
Textbook: Psychologists' psychotropic drug reference (pages 490, 491, 493)
Instant pharmacology book (page 279) Treat eating disorders (Bulimia nervosa),
Changes in appetite. Group Number 5 Group Co-ordinatior Dr. Amr Mahrous Trade name:
phenelzine / phenelzine sulfate
hydrazine monoamine-oxidase inhibitor
Mode of action: