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parkinsons disease ashley&bryn
Transcript of parkinsons disease ashley&bryn
SIGNS AND SYMPTOMS
stiffness/resistance to limb movement
decreased facial expression
LEWY BODIES FORM
First appear on the olfactory bulb, medulla oblongata, and the pontine tegmentum
May cause cell death, lysosomal
dysfunction and decreased mitochondrial activity
WHAT IS PARKINSON'S DISEASE?
Parkinson's disease is a degenerative disorder which is a result of the death of the dopamine-generating cells in your brain.
MUTATION OF GENES
appear in dead or dying dopamine-producing neurons
the most studied genes that cause PD are SNCA and LRRK2
SNCA makes the major component in Lewy Bodies
CURES AND TREATMENT
HOW IS IT INHERITED
Parkinson's disease can be inherited by the mother or father. It is dominant inheritance. It can be found on the x chromosome.
Parkinson's disease is not yet curable but medications are available to help with the symptoms.
There are therapies known to mimic dopamine but they don't always work and are expensive.
Lewy bodies are abnormal proteins that form
in the neurons of people with Parkinson's Disease.
Parkinson's disease affects mostly people over the age of 60
WHOM IT AFFECTS
Approximately one million adults in the U.S. have Parkinson's disease
Men are affected up to 2 times more than women
Young people still can be affected by Parkinson's Disease but it is very rare.
Lifestyle changes can help reduce your symptoms from the disease
Genetic testing is still very difficult and expensive but is available for individuals or families interested in learning if they will be affected by Parkinson's Disease in the future or if their future generations will be affected by it.
Many other complicated factors determine whether or not you will get the disease in the future but this gives a general idea if you or your family will be affected.
Heyn, Sietske N. "Parkinson's Disease." Ed. Melissa Conrad Stöppler. MedicineNet. WebMD, n.d. Web. 7 Mar. 2014. <http://www.medicinenet.com/parkinsons_disease/article.htm>.
Medical News Today. Alastair Hazell, n.d. Web. 7 Mar. 2014. <http://www.medicalnewstoday.com/info/parkinsons-disease/>.
National Human Genome Research Institute. Eric Green, n.d. Web. 7 Mar. 2014. <http://www.genome.gov/10001204>.
Symptoms of Parkinson's Disease are long term and may even get worse as time goes on. Life expectancy is still normal. Early death is usually only from a falling accident or pneumonia.