The Internet belongs to everyone. Let’s keep it that way.

Protect Net Neutrality
Loading presentation...

Present Remotely

Send the link below via email or IM


Present to your audience

Start remote presentation

  • Invited audience members will follow you as you navigate and present
  • People invited to a presentation do not need a Prezi account
  • This link expires 10 minutes after you close the presentation
  • A maximum of 30 users can follow your presentation
  • Learn more about this feature in our knowledge base article

Do you really want to delete this prezi?

Neither you, nor the coeditors you shared it with will be able to recover it again.


Stem Cell Factor/ c-kit system: a molecular enhancer of metastasis from prostate cancer?

ISCOMS Oral Presentation

Alejandro Jiménez

on 14 December 2012

Comments (0)

Please log in to add your comment.

Report abuse

Transcript of Stem Cell Factor/ c-kit system: a molecular enhancer of metastasis from prostate cancer?

Alejandro Jiménez-Sánchez

National University of Mexico Stem Cell Factor/c-Kit system:

a molecular enhancer of metastasis from prostate cancer? Prostate Cancer Statistics Hormone Therapy


Radiation Therapy

Chemotherapy Prostate Cancer Stages Migration Clonogenicity Survival Metastatic
Cancer Cell
Behaviour Invasion Proliferation Metastasis The Project Cell lines c-Kit expression Migration Clonogenicity Mwm K562 DU145 PC3 HaCat RT-PCR Western Blot (cc) image by anemoneprojectors on Flickr Mwm K562 HaCat DU145 PC3 c-Kit 289pb c-Kit 145kDa GAPDH 37kDa 400 pb kDa 300 200 181.8 115.5 37.1 * * ** P<0.01
P<0.05 ** * ** ** P<0.01 ** P<0.05 * * * * * ** Proliferation * The Stem Cell Factor alone does not enhance the migration and clonogenicity abilities which are crucial steps for the whole metastatic behaviour.

However, Stem Cell Factor increases the proliferation rate of prostate cancer cell lines. Conclusions Stem Cell Factor/c-Kit system + Proliferation NO
Migration NO Clonogenicity (cc) photo by medhead on Flickr Jemal A. Global Cancer Statistics. (2011) National Cancer Institute (2012) J. L. Spivak. The Anemia of Cancer: Death by Thousand Cuts. (2005) National Univeristy of Mexico

Leticia Rocha Zavaleta (supervisor)

Cecilia Aguilar (technical support)

Tzipe Govezensky (statistical support) Acknowledgments Proliferation


Full transcript