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Medical Applications of Nanomaterials
Gregory Nicolason 16 June 2013
Transcript of Medical Applications of Nanomaterials
Biotechnology meets Nanotechnology
used as a building material for the nano-matter
Fastest growing field of research across the globe
Presents sate of the art research in biomedical and also considers the socio-political risks and perception of an important science
Nanomedicine is the medical application of nanotechnology.
There are a variety of applications they range from the medical applications of nano-materials such as artificial nano-sized "building blocks" to asset in the healing of broken bones to future applications of molecular nanotechnology.
Nanomedicine is a large industry, in the year 2004 sales involving nano medicine reached almost 7 billion dollars, this includes 200 companies and almost 40products worldwide. it is also estimated that almost 4 billion dollars in research and development are invested every year.
So much investment , thus it has astonished governments and business men. How ? throughout this presentation you will discover how this type of science grew to be the fastest and largest industry in history.
Nanodrugs and Drug Delivery
Prostheses and implants
Examines developments in three sub-fields:
-Nanodrugs and Drug delivery
-Prostheses and implants
- Market and Future Development
The artificial red-blood cell, or “respirocyte”, proposed here is a blood-borne, spherical, pressure vessel with active pumpingonboard, remotely reprogrammable nanocomputer; and chemical and pressure sensors.
Considering that cancer is the number one killing disease in the world
Thus with a greater, broader development in nanotechnology – specifically the medical field – researchers can find new ways to tackle the impacts of cancer throughout our society. It would/could be, one of the greatest achievements
Technical applications with cancer
How can this be done
Nanotechnology is playing an increasingly important role in molecular imaging and therapy.
The use of a molecularly targeted nanoplatform affords many advantages over conventional approaches. --> For Imaging
thousands, or even more imaging labels
or a combination of labels for different imaging modalities can be attached to a single nanoparticle, which can lead to dramatic signal amplification.
Second, multiple, potentially different, targeting ligands on the nanoparticle can provide
enhanced binding affinity and specificity
How to remove tumor ?
Iron particles are magnetized then inserted into the fastest pathway to the tumor. The nanoparticles are then directed exclusively toward the affected cells by using a specific type of external magnet or by attaching the magnetized particles to “ cancer-seeking” biological agents .
Once the nanoparticles are in place inside the tumor they can be heated, killing any and all cells in their vicinity, in turn killing the cancer.
The heating is created by rapidly changing magnetic field generated by a hand-held paddle-shaped device, known as the MACH ( Magnetic Alternating Current Hyperthermia) machine.
Nanoparticles are defined as small objects that behave as a whole unit in terms of their transport and properties.
There are several methods for creating nanoparticles, including both Attrition and Pyrolysis.
Attrition is a form of erosion. The regular impacts between two objects cause them to be broken up into smaller fragments.
Pyrolysis is a thermochemical decomposition of organic material at elevated temperatures in the absence of oxygen.
Iron particles are magnetized
air classified to recover any and all nanoparticles
A great advantage is that magnetic resonance imaging (MRI) scan can be carried out to map exactly where the particles go in the body
Most popular/known form of biomedical nanotechnology is Tissue Engineering and growth of new organs.
Tissue engineering is based on the creation of new tissues in vitro followed by surgical placement in the body or the stimulation of normal repair in sito using bioartificial constructs.
Nanoscale building of cells can be accomplished by their programmed replication. The signals are transmitted back and forth with the instruction for the desired size and shape from the construction site. When complete instructions are finished, the organs can be grown according to the prerequisite specifications.
Market and Future Development
Types of sensor entering the market:
-Lab-on-a-chip diagnostic techniques.
-Sunscreens with ultraviolet-light absorbing nanoparticles.
Report also said the following applications are expected in the next decade:
-Longer-lasting medical implants
.-The capability to map an individual’s entire genetic code almost instantaneously
-The ability to extend life by 50% from present expectations.
Nanotoxicology is the study of the toxicity of nanomaterials.
This room achieves the world's highest cleanness levels and moisture control.
cleanliness levels can be adjusted to enable verification of the clean environment required by each scientist.
Not even your mother would like to live in it
Neelina Malsch, Malsch TechnoValuation. Date MAy, 1, 2013 http://www.nanoscienceworks.org/publications/books/imported/0824725794Richard Feynman
“Six Easy Pieces”.Addison-Wesley Pub. Co., Mento Park, CA, 1963. http://www.azonano.com/article.aspx?Article1D=1242 By Ineke Malsch
Biomedical Applications of Nanotechnology, May, 1.2013 http://www.aip.org/tip/INPHFA/vol-8/iss-3/p15.pdf
Advectus. The company is in fact the holder of exclusive worldwide rights on the delivery and production of drugs that are used in fighting brain cancer and tumor.