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elizabeth carrillo

on 14 January 2015

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Transcript of T-cell

what ligand attaches to T-cells?
What Kind of
Receptor is It?
This is a T-cell receptor. It is a molecule found on the surface of T-cells that is responsible for recognizing antibodies attached to Major Histocompatibility Complex (MHC) molecules.
Pathway of the T-cell
The TCR (T-Cell Receptor) is made up of membrane proteins that help T-Cells in their response to the presentation of antigen or abnormalities. Stimulation of TCR is triggered by MHC (Major Histocompatibility Complex) molecules that assist in the detection of antigens and signals TCR complexes and start a series of intracellular signaling or different cell signaling cascades. Engagement of the TCR initiates positive and negative cascades that ultimately result in cellular growth, differentiation, Cytokine production, and/or activation-induced cell death.
Cellular and Organism Response
Cellular Response: It helps out in B-cell activation. It transmits signals directly to the cell's interior when it binds to small proteins. The MHC class is recognized by T-cells , by telling them to make proteins, which causes the B-cell to multiply
By: Elizabeth Carrillo, Alaysia Brandy, Marissa Alcala, and Amani Nimer
T-cells are a type of white blood cells that move around the body searching for cellular abnormalities.
They regulate the immune system.
The Major Histocompatability Complex (MHC) is the normal protein on the surface of the cell and when the an abnormal peptide attaches to the molecule and it triggers the process of a T-cell as the cell feels threatened.
Correct Mechanism
If the mechanism of the T-cell follows through without any blockage the T-cell will attack the area of abnormality found in the body and kill it.
Faulty Mechanism
If the process fails
If the killer t-cell doesn't get to the infection or virus the abnormality will build up and cause a disease in the host.
*B-cell: a type of white blood cell, and specifically a lymphocyte. ( a blood cell that is the fundamental importance of the immune system
There are two types of t-cells: helper cell and killer cell. The killer t-cell destroy the infection and the helper t-cell assists the attack.
Organism Response: Without t-cell, it would cause many disorders in the body. It happens when the thymus is absent. These disorders may include immune dysregulation and it may end up being lethal in the body.
Current Research
Types of T-cells
Today t- cell studies are deep in research associated with cancer. Scientist are trying to develop ways to increase ones immunity to protect the body from further harm. This of course would greatly benefit cancer patients as their immunity is extremely low.
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