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Transcript of Cannabis
"The Bliss Molecule." General Chemistry Online! . Fred Senese, 15 Feb 2010. Web. 1 Dec 2013. <http:// antoine.frostburg.edu/chem/senese/101/features/anandamide.shtml>.
"drug use." Britannica School. Encyclopædia Britannica, Inc., 2013. Web. 30 Nov. 2013. <http://school.eb.com/levels/high/article/110090>.
"Marijuana." Drugs and Controlled Substances: Information for Students. Ed. Stacey L. Blachford and Kristine Krapp. Detroit: Gale, 2011. Student Resources in Context. Web. 1 Dec. 2013.
"marijuana: facts for teens." Pamphlet by: National Institute on Drug Abuse. National Institute on Drug Abuse, 1998. 1. Student Resources in Context. Web. 1 Dec. 2013.
"tetrahydrocannabinol." Britannica School. Encyclopædia Britannica, Inc., 2013. Web. 30 Nov. 2013. <http://school.eb.com/levels/high/article/71857>.
active hallucinogenic component of marijuana
strength and potency of THC (along with growth, harvest, and storage) affects the response after smoking cannabis
absorbed into fatty tissue in organs for several days - few weeks
Effects of Cannabis
- Rapid heart rate
- Increased BP and breathing rate
- red eyes, dry mouth
- slowed reaction time
- the "munchies"
Neurons and Neurotransmitters
dried, shredded leaves, stems, seeds, and flowers of the cannabis plant
over 200 slang names
Sinsemilla, hashish ("hash"), and hash oil - stronger forms
400 + chemicals
pain, depression, appetite, memory (forgetting), and fertility
similar 3-D shape
Anandamide breaks down faster, shorter high
The Bliss Receptor
1988 - receptors found for THC
not naturally in the body, mimicked natural receptor key
1992 - natural key found
withdrawl can lead to:
- decreased appetite
- anxiety and aggression
similar biological activities
similar feature orientation and arrangement
1. What is the active hallucinogenic in cannabis?
3. THC mimics which neurotransmitter?
4. What does the neurotransmitter that THC mimics affect?
a. I only
b. I and II
c. I and III
d. II and III
e. I, II, and III
-Neurons process information
-Neurotransmitters allow for communication
-Neurotransmitters bind to protein receptors and are chemicals that change electrical charge , allowing various functions to be turned "off" and "on"
- thousands of receptor
-foreign chemicals can block or mimic neurotransmitters
- Typically with neurons, there is a "refractory" period
Cannabinoids: Specialized neurotransmitters released just after neurons fire
Cannabinoids REMOVE this period. THC actively binds with Cannabinoid receptors - produces high from mimicking Anandamide, increasing pleasure.
levels of dopamine and norepinephrin also increase!
a. 1 and 3
b. 1 and 2
c. 1 only
d. 2 only
e. all of the above
c. inhibitory neurotransmitter
a. shallow breathing
b. decreased heart rate
5. What does THC block?
6. What is one effect of using Cannabis?
2. Where in the brain is the concentration of
Cannabinoid receptors greatest?