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Transcript of osteogenesis imperfecta
helena background info 1. OI can be an inheritaoe disease from your parents. 2. 50% chance of passing the disorder
to his or her children.
new reasecrch findings ◦Muscle weakness
◦Pulmonary diseases in effected people
◦Below average height
◦Defects in gene that produces callogen 1
◦Blue tint to the white of the eye
◦Loose joints 1. 10-15% of OI cases result in a recessive mutation 2. alcohol, smoking, high amounts of caffiene consumption, and unhealthy weight can make bones even more fragile 3. 50% chance of passing the disorder to his or her children. 4. OI can be an inheritable disease from your parents ◦Physical therapy
◦casts, splints, braces, etc. for broken bones.
◦Surgery, to input rods in the bone to support the bone.
◦Bone strengthening medication.
◦using canes walkers and wheelchairs. area most common by bone cancer *eyes http://en.wikipedia.org/wiki/Osteogenesis_imperfecta *knees & legs *feet & ankle *spine & neck * arm,elbow & shoulder * hand & wrist * hips http://www.endotext.org/parathyroid/parathyroid17/index.html The term osteogenesis imperfecta (OI) is used for a group of disorders in which genetic defects result in abnormally brittle bones that fracture easily. A number of types have been described based on the severeity of disease. This group of disorders is also known as ‘brittle bone disease’. by: 3.) An estimated 20,000 to 50,000 people in the US have this disease. OI can affect males and females of all races. Hopkins Children's we hope for the best for OI! http://disorders.eyes.arizona.edu/handouts/osteogenesis-imperfecta Genetics Home Reference time to fly to facebook and prezi 5. There are 8 types of OI