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Booming Biotech Industry

BUS 4077 Final Presentation
by

Lina Luong

on 30 November 2012

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Transcript of Booming Biotech Industry

Screening (Chemistry) Benjamin Whiteman
Heidi Hart
Lina Luong
Rudy Duran
Samantha Soroten Biotechnology
"Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use."

-United Nations Convention on Biological Diversity Biotech Definition •Industry characteristics & culture
•Life-cycle management
•Supply-chain
•Import/export profile
•Geographical markets
•Major Players ROADMAP Biotech Industry Displays Rapid Growth The Life Cycle Management of Bio Tech Businesses can be broken down into four basic steps. The synchronization of these steps is what separates successful Bio Tech firms from competitors. The four steps in order are: discovery, product development, manufacturing, and sales. Life Cycle Management Supply Chain Changes Pace Product Life Cycle Contains Many Processes Product life cycles are shortening and pace of product introduction is accelerating

Importance in speed to market, scalibility, and regulatory knowledge

Need quick distribution and operational efficiency Medicine Agriculture Biological Engineering Research
Discovery
Product Cycle
Testing
FDA Process
More testing, if needed
Manufacture
Marketing The US Leads The Biotechnology Industry  Top regions for biotechnology
North America
Europe A Rising Superpower And The World’s Most Populous Country  China: 
On the path to becoming a significant biotech player
Government reform
Investment and growth
Investors seeking opportunity
life sciences venture capital and private equity investments exceeded US$1 billion in 2010
63% of that total directed at biopharmaceutical enterprises Countries Reaching For Growth  India: 
Innovation opportunities
Molecular diagnostics
Personalized medicine
Government
A key role in supporting the industry
Opportunities ahead
Increased financial assistance and opportunities
Investment of multinational companies
Biofuels segment promises large scale expansion Slowly Emerging From The Global Financial Crisis New Zealand:
Growing awareness of the impact of biotechnology across many industries
Government emphasize the importance of biotechnology
Asian investors: increased interest
Direction of New Zealand biotechnology will be shaped by the country’s ability to cater to the needs of emerging markets, including China
US$18 million investment by Chinese venture capitalists
New Zealand’s free trade agreement with China has in part paved the way for wider investment in biotechnology
Agricultural activities and food-related biotech Exploring New Opportunities Singapore:
Ranked globally as the easiest country in which to conduct business
Preferred biomedical research and manufacturing destination
Strong intellectual property protection
Strategic location
Modern infrastructure
Quality workforce Laying The Foundation
For Innovation Japan:
A strong history of innovative R&D
The world’s second-largest pharmaceutical market
Strong government support
Pro-industry regulatory reforms
Global financial crisis was a significant setback
Japan’s pharma companies seek to expand their geographic footprint, pipelines and product offerings. Biotech Industry:
Country Profiles Fueling Growth With
Investments And Reform Brazil:
Brazil has a leading position in agricultural biotech and biofuels
Strong natural resource
Investments in biofuels
Global oil majors are becoming increasingly interested in the
green-energy potential that Brazil has to offer
Agricultural biotech
Already the world’s second-largest biotech crop-cultivating country
Biopharmaceutical players
On the expansion track
Government policy
Industrial policies focused on encouraging innovation Biotech Industry Leaders Shire Plc. Takes Biotech Industry Lead 5,250 Full Time employees
Headquarters in Dublin, Ireland
Organized into three divisions: Specialty, Human Genetic Therapies, and Regenerative Medicine
Product portfolio:29
ADHD
Constipation
Narcolepsy
Eating Disorder
Depression
And more Shire Spans the Globe Offices in over 29 countries
Products marketed in over 50 Shire: Enabling Higher Quality of Life "We're proud to be one of the world's leading
specialty biopharmaceutical companies, but
we're even more proud of the difference we
make to the lives of people with life-altering
conditions." Sun Pharmaceuticals Industry Rises Headquarters: Mumbai, India
Serves over 40 countries
Since 1983
Largest market: United States
Product Portfolio: Pipeline of over 2600 products of which 1600 are registered and marketed
Cardiology
Psychiatry
Neurology
Gastroenterology
Diabetology
etc. Gilead Sciences Since 1987 Gilead Sciences has worked to discover, develop and commercialize medications to advance the care of patients suffering from life-threatening diseases in areas of unmet medical need.
Approximately 4,500 Employees
Headquarters: Foster City, California
Product Portfolio:14
HIV/AIDS
Hepatitis
Respiratory
Cardiovascular
Metabolic conditions
Cancer
and
Inflammation. BTG Plc Mission: To bring to market medical products that meet the needs of specialist physicians and their patients, and in doing so to build a sustainable, profitable business that delivers superior returns to our shareholders.
Full Time Employees: 330
Headquarters: London, England
Product Portfolio: 3
Blood Toxicity
Antivenin
- Around 10% of existing drugs originate from biotech research

- More companies are trying to outsource supply chain operations

Expansion outside of traditional pharm production geographies

- Provision of raw materials for experimental purposes

Experiments require small quantities of material

- Technology is needed to execute research efficiently and effectively R&D Requires Limited Materials Regulations Monitor Product Development
- Drugs are heavily regulated for safe consumption
Many compounds are screened in first PD stages, but few make it through whole cycle

FDA creates approval and studies are still continued to explore drug’s capabilities

- Regulations on execution, facilities used, and worker aptitude Manufacturing Creates Products - Creating placebos for clinical trials and production for market

- Made into pills, ointments, vials, and other forms

- Pharm manufacturing: chemical synthesis

Active ingredient in drug is created according to formula

Tempered under controlled heat and conditions that need supervision

- Biopharm manufacturing: cell-culture

Ingredients are purified and then formulated Product Sales - Prescription:
Medical Practitioners
1 on 1 Consultations
Promotional Literature
Conferences
- Over the Counter (OTC)
Consumers
TV Advertising
Internet Advertising
Publication Materials
- Customer Support Discovery (cc) image by nuonsolarteam on Flickr - Packaging and storing are done by warehousing, pharmacies, and other places depending on manufacturers

- Distribution targeted towards doctors and consumers

- After patents expire, generic brands may branch off Products Become Ready for Market Biological
Target Identification Biological Target Validation (cc) image by nuonsolarteam on Flickr Optimization (Chemistry) Legal Documentation Optimization (Chemistry) Phase II Product Development (cc) image by nuonsolarteam on Flickr Pre-Clinical
Trials Phase I (cc) image by nuonsolarteam on Flickr Phase III Submission for Approval/Preview Phase IV (cc) image by nuonsolarteam on Flickr Manufacturing (cc) image by nuonsolarteam on Flickr Chemical
Synthesis Storage (cc) image by nuonsolarteam on Flickr Transportation Logistics Purification Formulation Development Dosage Form Manufacturing Packaging Manufacturing Creates Products - Creating placebos for clinical trials and production for market

- Made into pills, vials, ointments, and other forms

- Pharm manufacturing: chemical synthesis
Active ingredient in drug is created according to formula

Tempered under controlled heat and conditions that need supervision

- Biopharm manufacturing: cell-culture
Ingredients are purified and then formulated - Packaging and storing are done through warehousing, pharmacies, and other places, depending on manufacturers

- Distribution is targeted towards medical practitioners and consumers

-After patents expire, generic brands may branch off Products Become Ready for Market
Full transcript