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Copy of Depression

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by

esraa mostafa

on 31 March 2015

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Transcript of Copy of Depression

Mode Of Action
PAROXETINE
By: Group 5
What is paroxetine ?

( In treatment of)

1)
Depression
2) Anxiety disorders
3) Premenstrual dysphoric disorder (
PMDD
)
4) Eating disorders
5) Pain disorders
USES
Precautions & contraindications
Drug-drug interaction
With :
pimozide


Serotonergic Drugs


MAOIs


Warfarin


**
Inhibit cytochrome p45o
If used during the last 3 months of pregnancy develop withdrawal symptoms such
seizures
, muscle stiffness, or
constant crying


passes into breast milk.


It may harm an
unborn baby
(birth defects) = may lead to Persistent Pulmonary Hypertension (PPHN)
.
Precautions cont.
There's No Drug 100% Safe So
Department of Pharmacology and Toxicology

Pharmacology II

Drug Profile 10

A Decade of Achievements
Adverse Effects
1- GIT disturbance
2-
sexual dysfunction
3- sleep disturbance
4- weigh gain
5- discontinuation syndrome
1-
pregnancy
& lactation

2- epilepsy , renal impairment, glucoma

3- don't use under the age of 25

4-
serotonin syndrome


1-
serotonin syndrome

2- epilepsy , renal impairment, glucoma

3-
pregnancy
& lactation

4- don't use under the age of 25
Full transcript