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By Lindsey Palumbo pd3

Lindsey Palumbo

on 19 November 2012

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Transcript of Hemophilia

By Lindsey Palumbo Pd3 Hemophilia Physical and Mental Symptoms Many large or deep bruises
Joint pain and swelling caused by internal bleeding
Unexplained and excessive bleeding or bruising
Prolonged bleeding from cuts or after surgery
Nosebleeds without a known cause
Tightness in your joints
In infants, unexplained irritability
Unusual bleeding after immunizations Internal and External Parts of the Body that are Affected by Hemophilia and who is affected: circulatory system
Musculoskeletal system
Digestive system
male particularly have the disease more often than females What is Produced When the Body has Hemophilia The disorder causes the blood not to clot because the blood is too thin and won't turn from a liquid to a solid to stop the bleeding. The Limitations Of Hemophilia Contact sports such as football or wrestling are prohibited because of the high risk of bleeding, swelling, head or neck injury. What Equipment, and Medications the Affected Person Needs blood donations are purified. they may be produced by genetic engineering
One medication that should not be used by those with hemophilia is aspirin, a pain reliever, since it interferes with normal blood clotting.
A medication called DDAVP can also be used. How these Treatments Will Help The Person can have a temporary treatment from the lack of clotting
It will prevent bruising and excessive bleeding in minor injuries . Life Expectancy The life expectancy is 75 years. And unfortunately, the disorder cannot be cured. This shows the possible outcomes of a child between a male and female. If you look to the right, you see an example of a Punnett Square. The male is at the top of the square, and has hemophilia because his one "x" chromosome has the disease. The female is completely clean from the disease. x= carrier
Y=not carrier
H=person with hemophilia How the Disorder is Inherited The gene is recessive and is sex-linked.
The disease is located on F8 gene. Queen Victoria, passed Hemophilia to her three kids. And due to its presence in the royal families of Europe in the 18th and 19th century, hemophilia came to be known as the "Royal Disease".
John Conrad Otto was the very first to discover this genetic disorder in 1803.
There are three levels of Hemophilia: Mild, Moderate and severe.
There are different types of Hemophilia that affect different blood types. Facts: Continued... This disorder isn't common. it happens to 1 in 10000 males Hemophilia affects many more males than females because the mutation appears on the x chromosome which the male receives from his mother, he doesn't have a normal gene on the Y chromosome to compensate it so he has the disorder. Sources ghr.nlm.gov/condition/hemophilia
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