Loading presentation...

Present Remotely

Send the link below via email or IM


Present to your audience

Start remote presentation

  • Invited audience members will follow you as you navigate and present
  • People invited to a presentation do not need a Prezi account
  • This link expires 10 minutes after you close the presentation
  • A maximum of 30 users can follow your presentation
  • Learn more about this feature in our knowledge base article

Do you really want to delete this prezi?

Neither you, nor the coeditors you shared it with will be able to recover it again.


The elderly gut microbiota

No description

Merle van Cranenbroek

on 23 January 2015

Comments (0)

Please log in to add your comment.

Report abuse

Transcript of The elderly gut microbiota

What determines microbiota composition of elderly subjects?
What are the main microbiota differences between young and old individuals?
What is meant by inflammaging?
The microbiota in infants is highly dynamic
Change in:
Low-grade chronic form of inflammation
reduced intestinal motility
reduced dentition
reduced salivary function
reduced chewing strength
increased intestinal permeability
The elderly gut microbiota
Based on the article of Claesson et al. 'Gut microbiota composition correlates with diet and health in the elderly' 2012
Thank you for your attention!
Risk for the elderly:
Senescence of cells
damaged cells
harmful product of microbiota
Potential inflammatory diseases:
bowel diseases
Diabetes Mellitus (type II)
Firmicutes most dominant in young adults
residence location
Composition destabilizes again in elderly
Decrease in abundance of firmicutes in elderly
intrinsic factors involved in eating and digestion:
possibly also: climate, culture and extreme environment
Full transcript