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Pedigree Charts and Karyotyping

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Jeffrey Mann

on 29 April 2013

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Transcript of Pedigree Charts and Karyotyping

We have seen how complicated genetics can be. There are may ways in which genetics can make a mistake and cause health problems. Genetics III:
Pedigree Charts and
Karyotyping Pedigree Charts Pedigree Charts Pedigree Charts In this section, we will discuss how scientists trace and identify genetic traits that can cause disease. One way of studying genes in humans is to use a tool called a PEDIGREE CHART. It helps people to understand how traits are inherited. In a pedigree chart the family linage and a specific trait is illustrated. In pedigree charts: Female = Male = Since pedigree charts trace traits through family lineages family relationships are described like this: Marriage: Offspring: In this pedigree chart, how many children are there? Four How many are BOYS? ONE How many are girls? THREE Pedigree Charts A person who has the dominant trait: or A person who has the recessive trait: or Let's look at one family and describe who can taste PTC and who cannot: t t T T T T T How many parents were NOT PTC tasters? How many offspring were NOT PTC tasters? Karyotyping Karyotyping is when geneticists look at chromosomes to get clues if there is genetic abnormality. Many diseases can be detected by karyotyping. Let's Try Karyotyping. To "read" a set of human chromosomes, scientists first use three key features to identify their similarities and differences:

Size. This is the easiest way to tell two different chromosomes apart.

Banding pattern. The size and location of Giemsa bands on chromosomes make each chromosome pair unique.

Centromere position. Centromeres are regions in chromosomes that appear as a constriction. What you need to know:
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