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What makes expanded-Polytetrafluoroethylene (ePTFE) suitable for vascular grafts?

My physics coursework in which I analyse the macroscopic features of a material ,for a specific use, and how
by

Daniel Hammocks

on 31 January 2013

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Transcript of What makes expanded-Polytetrafluoroethylene (ePTFE) suitable for vascular grafts?

What Makes Expanded-Polytetrafluoroethylene Suitable For Vascular Grafts? By Daniel Hammocks Biocompatible
Lightweight
Resistant to Kinking
High Pressure Threshold
High Chemical Resistance
Non- Biodegradable Material
Low Friction Coefficent
Durable
Infection Resistant
Low Thrombogenecity
Non-Toxic
Flexible
Will Not Cause Carcinogenesis
Will Not Cause Hemolysis Manufacturing Process Introduction Why Use Expanded What properties do vascular grafts need? References [1] http://en.wikipedia.org/wiki/Tetrafluoroethylene
[2] http://en.wikipedia.org/wiki/Chloroform
[3] http://en.wikipedia.org/wiki/Hydrogen_fluoride
[4] http://en.wikipedia.org/wiki/Pyrolysis
[5] http://www.gdrc.org/uem/waste/swm-glossary.html
[6] http://www.sks-bottle.com/Plastic_Glossary.html
[7] http://en.wikipedia.org/wiki/Polytetrafluoroethylene
[8] http://www.jvascsurg.org/article/S0741-5214(12)00252-2/abstract
[9] http://www.surgical-tutor.org.uk/default-home.htm?tutorials/graft.htm~right
[10] http://www.ncbi.nlm.nih.gov/pubmed/10685063
[11] http://dspace.mit.edu/handle/1721.1/32727
[12] http://www.nlm.nih.gov/medlineplus/ency/article/007394.htm
[13] http://www.meetcongress.com/pdf/meet2008/THURSDAY%20JUNE%2026/SESSION3/16.50-FARBER.pdf
[14] http://emedicine.medscape.com/article/461285-overview
[15] http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002415/
[16] http://en.wikipedia.org/wiki/Aortic_aneurysm
[17] http://www.ncbi.nlm.nih.gov/pubmed/18603048
[18] http://cardiacsurgery.ctsnetbooks.org/cgi/content/full/3/2008/1277?ck=nck
[19] http://www.gore.com/MungoBlobs/827/932/ExpandedPTFEandTheirMembranes_Gore_Chapter23_Feb2008.pdf
[20] http://www.steadyhealth.com/articles/The_Horror_of_Toxic_Pans__The_Dangers_of_Teflon_a1512.html
[21] http://www.microcare.com/faqdetails.aspx?faqid=77
[22] http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002415/
[23] http://en.wikipedia.org/wiki/Thrombogenicity
[24] http://www.vascutek.com/vascutek/technology
[25] http://www.gore.com/en_xx/technology/creative/technical_capabilities.html
[26] http://www.vascutek.com/vascutek/technology
[27] http://en.wikipedia.org/wiki/Polyethylene_terephthalate
[28] http://www.matbase.com/material/polymers/engineering/pet-bottle-grade/properties
[29] http://www.a-levelphysicstutor.com/matter-props-defns.php
[30] http://hypertextbook.com/facts/1999/IrinaVinar.shtml
[31] http://core.materials.ac.uk/search/detail.php?id=2773
[32] http://www.matbase.com/materials/natural-and-synthetic-polymers/engineering-polymers/material_properties_of_ptfe.html
[33] http://www.uweb.engr.washington.edu/research/tutorials/ptfe.html
[34] http://www.chemistry.org.il/booklet/22/pdf/ilana_cohen.pdf What is a vascular graft?

How can vascular grafts be used? Computerised Image Showing Arterial Replacement in Upper Arm Arterial Bypasses Aortic Debranching Arterial Replacement Arterial Replacement
In Lower Arm Computerised Image of Arterial
Replacement and E(PTFE) Polymer
Chains Poly(tetrafluoroethelyene)? How do we make expanded-Poly(tetrafluoroethylene) from Poly(tetrafluoroethylene) ???? Poly(Tetrafluoroethylene) Biocompatible
Lightweight
Non-Toxic
Durable
Resistant to Kinking
Flexible
Low Friction Coefficent Infection Resistant
Low Thrombogenecity
High Pressure Threshold
High Chemical Resistance
Non- Biodegradable Material
Will Not Cause Carcinogenesis
Will Not Cause Hemolysis Why Use EPTFE Over Other Similar Materials? Expanded-Poly(Tetrafluroethylene) Is Under Patent and Therefore Data is Approximated From Poly(Tetrafluoroethylene) Poly(ethylene terephthalate) and Polyurethanes are the two other materials which dominate the vascular graft market, mainly for their chemical stability, resistance to degradation. They are also biocompatible and hemocompatible. Images (1) http://ars.els-cdn.com/content/image/1-s2.0-S0741521412002522-gr4.jpg
(2) http://www.goremedical.com/resources/images/popups/vgavaccess.jpg
(3) http://www.goremedical.com/resources/images/popups/hybrid.jpg
(4) http://www.vascutek.com/vascutek/technology
(5) http://4.bp.blogspot.com/_IoU3bEFUwWc/TCZ57mjFMKI/AAAAAAAAJJg/5WbEC0j6its/s400/Polytetrafluoroethylene.jpg
(6) http://www.meetcongress.com/pdf/meet2008/THURSDAY%20JUNE%2026/SESSION3/16.50-FARBER.pdf
(7) http://www.gore.com/en_xx/products/medical/surgical/vascular/vascular.html
(8) http://www.goremedical.com/hybrid/ (1) (3) (6) (6) (3) (7) (8) (8) (4) (5) [27/28/31] All Material Selection Charts Are From Reference [31] [14/16/18] [1/2/3/4/7/24] [12] [22] [25/32/33]
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