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Celiac Disease

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on 18 February 2015

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Transcript of Celiac Disease

What is Celiac Disease?
People with Celiac Disease, also known as Gluten-Intolerance, cannot eat gluten, a protein found in wheat, rye and barley, without triggering an immune response that attacks the small intestine. The villi on the small intestine are damaged so that nutrients aren't properly absorbed. (What is Celiac Disease?)

Gene Mutation
Gene mutations such as HLA-DQ2 and HLA-DQ8 on chromosome 21 increase the risk of developing CD; however, having these mutations doesn't mean you will have CD. (Celiac Disease) Approximately 30% of Caucasions carry these alleles, but only 5% of people with them develop CD because other factors must be involved. (Genetics of Celiac Disease)
Symptoms can vary greatly according to the person. Some of the most common are:
weight loss
loss of bone density
abdominal bloating and pain
(Celiac Disease)
First Signs of Symptoms
Where is CD most commonly found?
Celiac Disease is most common in the Irish population and in Caucasians. "1 in 100 people in nearly every country in Europe including the Mediterranian Region, North Africa, and Asia are estimated to have CD." (Crowe, Sheila) The US, being a melting pot of many countries, has many citizens with CD.
By: Sylvia Cummings
Celiac Disease
There is no known pattern of inheritance for Celiac Disease and it is also neither dominant nor recessive. Celiac Disease is not sex linked, although it is hereditary; so a person's relatives who have Celiac Disease have a 1 in 10 risk of developing CD. (What is Celiac Disease?)
How is CD Inherited? Is it Dominant or Recessive and Sex-Linked?
In some cases no symptoms are shown at all because the undamaged part of the small intestine can absorb enough nutrients. When the villi are no longer able to absorb nutrients the first symptoms are shown. This usually occurs later in life. Others develop CD early and live with it for their entire lives. (Celiac Disease: Fast Facts)
The only known treatment to prevent the villi from furthur damage is a gluten-free diet which means eating no wheat, rye, or barley. People with CD often have deficiencies such as iron, calcium, and vitamin D, so a gluten-free multivitamin is taken. There is no pharmaceutical cure for celiac disease. (What is Celiac Disease?)
Support Groups
Celiac Disease Foundation-
"CDF supports the development of treatment for CD beyond the gluten- free diet." (Celiac Disease Foundation)

National Foundation for Celiac Awareness-
"NFCA advances widespread understanding of celiac disease as a serious genetic autoimmune condition." (Celiac Disease: Fast Facts)
<img src="http://celiac.org/wp-content/uploads/2015/02/celiac-logo-25.png" alt="Celiac Disease Foundation"/>
celiac.org/wp-content/uploads/ 2013/04/damaged-villi.png
Research Funding
I would like to fund the Celiac Disease Foundation which is currently working to advance CD research and provide patients with alternate solutions to a strict gluten-free diet. (Celiac Disease Foundation)

I would also like to get major supermarkets involved so that gluten-free foods are more accesible and less expensive.
I feel that CD needs to be considered a disease rather than a dietary condition. Gluten-free foods need to be more accesible. We need to make researching this disease a priority because so many people are affected by it.
Personal Thoughts
Works Cited
"Celiac Disease."
Mayo Clinic.
Mayo Foundation for
Medical Education and Research, 22 May 2013. Web. 11 Feb. 2015. <www.mayoclinic.org>.

"What is Celiac Disease?"
Celiac Disease Foundation.
Celiac Disease Foundation
2015. Web. 11 Feb. 2015. <celiac.org>.

"Celiac Disease: Fast Facts."
Celiac Central.
National Foundation for Celiac
Awareness, 11 Feb. 2015. Web. 11 Feb. 2015. <www.celiaccentral.org>.

"What is celiac disease?"
Genetics Home Reference.
U.S. National Library of
Medicine, Oct. 2011. Web. 11 Feb. 2015. <ghr.nlm.nih.gov>.

Fasano, Alessio. "Genetic of Celiac Disease."
WebMD LLC., 24 Aug.
2014. Web. 11 Feb. 2015. <emedicine.medscape.com>.

Crowe, Sheila. "What groups are at highest risk for Celiac Disease?" The New
York Times, 13 Jan. 2010. Web. 12 Feb. 2015. <consults.blogs.nytimes.com>.
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