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Retinoblastoma

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by

Jamie Lim

on 30 April 2014

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Transcript of Retinoblastoma

Retinoblastoma
Discovery
James Wardrop first found the tumor in one of his patients in 1809
Inheritance
RB1 gene (chromosome 13) controls cell division
If the gene is mutated, cells grow out of control and become cancerous
Not sex-linked
Is recessive
Diagnosis
An eye exam can diagnose retinoblastoma
Other tests may be conducted to determine the stage of the tumor or how far it has spread
Usually diagnosed at age 2
Symptoms
Pupil may appear white
Instead of a red eye from the flash, the pupil may appear white or distorted
Crossed eyes and eye pain
Can occur in one or both eyes
Affected Births
About 300 births are affected with retinoblastoma per year.
Retinoblastoma occurs mostly in children under the age of five.
Interesting Fact
Treatment
Options depend on the size and location of the tumor
Small tumors can be treated by laser surgery or cryotherapy
Enucleation may be required if the tumor does not respond to other treatments
Retinoblastoma is a rare type of eye cancer that develops in the retina, mostly in children.
Works Cited
Jamie Lim
Life Expectancy
If cured immediately, the child can have an average lifespan
Nearly 95% of children are cured, but they may lose an eye
Death caused by retinoblastoma is rare
Information:
http://www.csb-cde.ca.gov/documents/Causes%20of%20Visual%20Impairment/causes_retinoblastoma.htm
http://www.webmd.com/eye-health/eye-health-retinoblastoma-child-eyes
http://www.cancer.org/cancer/retinoblastoma/detailedguide/retinoblastoma-treating-general-info
http://ghr.nlm.nih.gov/condition/retinoblastoma
http://www.rbhouston.org/retinoblastoma.html
Images:
http://www.stjude.org/Images/misc-retinoblastoma-0602.jpg
http://www.gveyes.com/images/pe-retinoblastoma-01b.jpg
http://retinoblastoma.com/retinoblastoma/images/Cryo2.jpg
http://www.hinsdale86.org/staff/kgabric/Disease09/Retinoblastoma/Retinoblastoma%204.jpg
http://www.sarawakeyecare.com/Atlasofophthalmology/paediatric/bilateralretinoblastoma.jpg
Stages
Intraocular retinoblastoma
Extraocular retinoblastoma
Recurrent retinoblastoma
Unilateral
Bilateral
Cryotherapy
The RB1 gene is a tumor suppressor that blocks the excessive growth of cells
Other types of cancers are caused by the mutated RB1 gene, like brain tumors, leukemia, and lung cancer
Full transcript