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Fregoli Syndrome (Fregoli Delusion)
Transcript of Fregoli Syndrome (Fregoli Delusion)
(A.K.A. Delusion of Doubles) Presentation by:
Christian Krikke What is Fregoli Syndrome? belief that a person, usually someone the patient finds threatening is stalking them by disguising themselves as someone the patient knows.
Delusional Misidentification Syndrome
DSM-IV defines Delusional Syndrome as "false beliefs based on incorrect inference about external reality that exist despite the evident to the contrary and these ideas are not accepted by other members of their culture." Named after the Italian actor Leopoldo Fregoli
He was known for making quick wardrobe changes in a stage act
P. Courbon and G. Fail founded Fregoli Delusion in 1927
The first know person was a 27-year old woman from London who believed two actresses were pursuing her by disguising themselves as people she knew History Causes long term use of Levodopa or L-DOPA
when Levodopa decreases it causes delusions
Head Injury to the right frontal lobe and left temporoparietal lobes of the brain
lesions in the right temporal lobe and the fusiform gyrus
visual memory deficit
deficit in self-monitoring
deficit in self-awareness
deficit in cognitive flexibility
epileptic activity Symptoms Treatment Similar Delusional Misidentification Syndromes Capgras Syndrome
a person holds a delusional belief that a friend, spouse, parent, or other close family member has been replaced by an identical-looking impostor.
a person believes there is a double of themself doing there own independent actions
Mirrored Self Misidentification
a person believes their reflection is some other person
a person believes that people in their environment have switched identities but maintain the same appearance. The main form of treatment is pharmacotherapy.
Patients that show signs of other psychological disorders are usually prescribed Trifluperazine.
blocks dopamine receptors
Case #1 A 30-year old woman who had been in a car accident 8 years prior had been misidentifying strangers as people she knew. She misidentified a patient as her boyfriend, a nurse as her mother and the social worker as her sister. She was convinced her family was turned into strangers. Her EEG showed a spike and sharp waves in the left temporal lobe and her MRI was normal. She was treated with risperidone and her oxcarbazepine was increased to 900 mg twice a day. Her symptoms were completely resolved in a month. She had no memory of misidentifying people. Case #2 A 58-year old woman previously diaganosed with paranoid schizophrenia called the police stated there was a stranger in her home. When they arrived she said her husband was an imposter pretending to be her husband. They took her to a psychiatric hospital where she accused her doctor as being an imposter. She stated that a woman down the street from where she lived was stealing her things and replacing them with "old stuff." She was treated with Risperidone 2mg/day which improved her paranoid symptoms but not her Fregoli Delusion. When she was released she still believed her husband to be an imposter.