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Pellagra

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by

Jordie Shortie

on 20 February 2014

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Transcript of Pellagra

Pellagra
Pellagra
Primary Pellagra
occurs when a person does not get enough niacin (one of the B complex vitamins) or tryptophan (an amino acid)
Symptoms
‣ Delusions
‣ Diarrhea
‣ Inflamed mucus membranes
‣ Mental confusion
‣ Scaly skin sores
Cause
It's caused by having too little niacin or tryptophan in the diet. It can also occur if the body fails to absorb these nutrients
How it affects the body
The first sign is reddened skin with superficial scaling in areas exposed to sunlight, heat & friction.This may resemble a sunburn.
Skin
In time the skin becomes thick, hard, scaly and cracked
How it affects the body (cont.)
Lesions may occur anywhere on the body especially the hands, arms, lower legs, feet,
face, and neck (known as Casal's necklace)
Face
Lips, tongue and gums may be sore and peeling
Treatment
Primary- A high protein diet supplemented with B-group vitamins is needed for complete recovery
Treatment (cont.)
Secondary pellagra may be harder to treat in view of its possible causes.
Prevention
a diet adequate in niacin-rich foods, or appropriate supplementation
The first sign is reddened skin with superficial scaling in areas exposed to sunlight, heat & friction.This may resemble a sunburn.
Secondary Pellagra
Skin lesions may be treated with topical emollients
occurs when there is enough niacin in the diet but something prevents its absorption and processing
Cause
Chronic alcoholism
Prolonged diarrhea
Gastrointestinal diseases such as ulcerative colitis
Liver cirrhosis
Carcinoid tumors
Hartnup disease (tryptophan metabolism disorder)
Drugs e.g. isoniazid, azathioprine
If left untreated
◦Untreated pellagra will continue progressing over the course of several years, and is
ultimately fatal. Often, death is due to complications from infections, massive malnutrition brought on by continuous diarrhea, blood loss due to bleeding from the gastrointestinal tract.

by: Jordan,Maya&Amani
Full transcript