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NanoMedicine

bio-ethics project, concerning nano-medicine and its applications. research paper link: https://docs.google.com/document/d/1PMplGK0deJ9Xudew1Zz9EztN8C2gQfITS7ZFxBHCR8I/edit?usp=sharing
by

jenya Pryadkin

on 11 December 2013

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Transcript of NanoMedicine

NanoMedicine
BioEthics
Problems
The way I see the end goal for Nanomedicine, it is to provide a safe way to maintain top condition for a human system. There are very many difficulties in attaining that goal, and Dangers that may cause more harm than good to host humans.

Immuno-supression will cause increased danger to disease, and may cause the human affected to contract a disease that the nano-particles may be unable to prevent, and result in death.

Use of toxic materials, and inability to cope with the software will result in mutation, and a form of self-attack, where the body will start to attack the nano-medicine and cause a chain reaction, causing the nano-particles to either attack the new "enemy" cells, in a form of a theoretical immuno-disease.

clogging of tissue and blood vessels may cause death, stroke, loss of sight, defected sight, and other problems. Nano-particles must either reach a size where they are no longer dangerous in any way, or must have increased control at a certain point in the end of their life cycle.
Analyzing
Nano-medicine is a rapidly evolving science, and has the ability to alter the modern era of technology and medicine. It has fatal dangers, and the risks almost level up to the rewards. This is a dangerous and important new application of nanotechnology, that may further the human race as well as health, unimaginably if it is created successfully and is controlled effectively. failure rates may increase, and Even in testing stages, and animal experimentation, ethical dangers may halt research.

So, do you believe this field should be allowed to expand?
In my opinion, I believe that nano-medicine should be allowed to expand, but be put into effect only where it can be closely monitored and controlled effectively. it has fatal dangers, and the risks almost level up to the rewards. this product must be produced for quality. Even in testing stages, and animal experimentation, ethical dangers may halt research. Many, many threats must be addressed, and this subject must be thoroughly researched, and pushed much further. this field must be allowed to move on, and as well as before allowing for actual individual nano-medicines to take part in daily practices, nanomedicine is the gateway to a new stage of new ability, and a greater pool of knowledge about the inner workings of the human race. we may soon be able to: add another 30% to the average human life-span, eradicate wrinkles, and keep bone aand muscle structure from deteriorating with age. future generations may be able to live without knowing what its like to grow old or be sick, at all.

What problems do these dangers pose?
Breaking known information into analyzable segments.
Sourcing
http://www.nanotech-now.com/ethics-of-nanotechnology.html
http://connection.ebscohost.com/tag/NANOMEDICINE
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962275/
http://nanostandards.ansi.org/tiki-index.php?page=Published+Documents
http://www.nanoscience.ch/nccr/research/module_01
http://www.nanomedjournal.com/
http://www.nanomedicine.com/
http://www.futuremedicine.com/loi/nnm
One of the most exponentially growing fields in medicine and nanotechnology, nanomedicine is the application of tiny robots and modules that can and will potentially revolutionize the field of medicine, and the entire medical world. The applications of nanotechnology in medicine are limitless. However, there are also many threats, and faults in using nanotechnology in humans, that could lead to disaster. So, should we apply nano technology, and if so, under what circumstances?

How does this look like?
How far has this idea gotten?
link to Research paper
benefits
How can we benefit from Nano-Medicine?
With Nanomedicine we could improve the quality and length of a human life, as well as help eradicate multiple forms of disease. with more effective screening technology we can spot cancer, and other genetic and non-genetic disease in it's early stages, as well as treat it with nano-medical drug delivery systems that don affect the body the way some antebiotics and other more dangerous treatments do, like chemotherapy. Other nanobots will combat bacteria and viruses. in the future of this technology, nano-medicine may be able to erradicate wrinkles, remove fats from arteries, and extremely prolong the average human life-span. Future generations may be able to live without knowing the feeling of growing old, or being sick, at all.
Should we use nanotechnology?
Dangers
What is it similar to? What is it different from?

*Transparent nanocrystalline yttria-stabilized-zirconia calvarium prosthesis
(An extremely long way to say skull plate prostheses)

*research on the biomolecular corona needed to enter the cell.
(Cells semipermeable membrane needs to be tricked in order to allow entrance for the nano-device, this research allows scientists to input the device into a living cell, without it being destroyed.)

*Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor.
(Delivery system to administer drugs in order to diminish damage to the body system, to a liver tumor)

Even at the tiny size of 5 nano-metres, these particles can become compartmentalized in the peripheral tissues, and will gradually accumulate in the body over time. While advancement of research proves that targeting and distribution can be modified, and improved by nanoparticles, but this is still a very big setback, and danger for this technology.
By: Jenya Pryadkin
What is
Nano-Medicine?
Some current and ongoing projects include:
And if so, under what circumstances, and why?
What can we do with Nanomedicine?
Since this field has grown, scientists in this new industry have succeeded in creating nanostructures that look like, and mimic complex molecules. Some of these engineered structures may be able to potentially lead to therapies for conditions such as Alzheimer's, nerve injury and brain damage from stroke. Others have been able to convert these into structures that can inject and carry genes into stem cells. localized treatment, faster and more accurate diagnosis, and much less invasive procedures can be attained.
2 nano-drugs have been FDA approved, and are out on the market. These are Abraxane®, for breast and non-small-cell lung cancer, and Doxil® to treat treat ovarian cancer and multiple myeloma.
mice studies show that localized drug treatments were sucessful in minimizing cancer tumors.
soon, large scale nano-medicine may become a reality.
Nanomedicine, once fully developed, will be more effective than drugs. This is because nanobots cab always be present in the body, fighting off pathogens such as viruses and tumors. Nanorobots will not require any additional treatment and will become relatively cheap after their successful development.
Robotic white bloodcell attacking bacteria
localized treatment module
theoretical picture of future nano-medicine attacking pathogen
https://docs.google.com/document/d/1PMplGK0deJ9Xudew1Zz9EztN8C2gQfITS7ZFxBHCR8I/edit?usp=sharing
(in description)
video
conclusions
finalizing conclusions based on gathered data
Nanotoxicity is also an extremely threatening problem. many materials previously applied in nanotechnology will bring more harm to an organic organism than good. Using unsafe materials can result in cell death, triggered cancer and mutation in cell DNA, and ultimately death.
Immuno-suppression is a problem. the particles must be programmed to only attack bacterium that put the host into a certain degree of duress, in order to prevent immunosuppression, or failure of the immune system, and lack of a natural defense system, until nano-medicine and nano robots are fully able to take the place of the human immune system, which may be impossible.
Thank-you
for watching.

(Any questions will be answered now)
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