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Love

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by

Nora Klug

on 12 June 2017

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Transcript of Love

Love
under the Microscope

Physiological Effect
Female reproduction: facilitator of childbirth and breastfeeding
Sexual reproduction
Relaxation
Oxytocin
Hormone and neurotransmitter
Nanopeptide
Sum formula:
Produced in the hypothalamus
Discovery
Investment Game
Nasal spray of oxytocin
Increases trust

Hope: treatment of social disorders
1906 - Henry Dale discovered oxytocin in the pituitary
1953 - Vincent du Vigneaud isolated and synthesized oxytocin
Prairie vole
Montane vole
monogamous
polygamous
Source: nature, 2013

Example:
99% genetic identical,
but:
Chemical Messenger
Produced in the hypothalamus
Distributed by pituitary gland
Oxytocin receptors in different tissues of the body:
- Mammary gland
- Tissue of the heart, genitals, kidney, thymus, pancreas
- Adipocytes
Half-life: 1-6min


Oxytocin as a Medication
Conclusion
Sources
Outline
Source: nature, 2005
Example:

Accredited for use on pregnant women
to initiate childbirth
to induce labour
to prevent haemorrhage
to speed up abruption of placenta

'Off-label' use:
autism
other behavioural disorders







Oxytocin, das Hormon der Nähe (2016) Kerstin Uvnäs Moberg
http://www.nature.com/news/gene-switches-make-prairie-voles-fall-in-love-1.13112
http://www.nature.com/news/neuroscience-the-hard-science-of-oxytocin-1.17813
https://psychcentral.com/lib/about-oxytocin/
https://i2.wp.com/www.upinhealth.com/wp-content/uploads/2016/10/hypothalamus-and-pituitary.png
https://upload.wikimedia.org/wikipedia/commons/thumb/e/e3/Henry_Hallett_Dale5.jpg/220px-Henry_Hallett_Dale5.jpg
http://www.chemie.de/lexikon/Oxytocin.html
https://pubs.acs.org/cen/coverstory/83/8325/8325oxytocin.html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183515/
https://www.nature.com/articles/nature03701.epdf?referrer_access_token=iyA03EgRYYsqWpFcSUIEuNRgN0jAjWel9jnR3ZoTv0OSeVDAGS1CccKyFlI3yIpmnxNPvbBfjUQFE73qhpeYxw5A-PZl24p-HNGBkk-NYXuU0XWy5xjeF1kv4P04iAyfQk2l0lYR4_4hk8OBhY3DieLJOAmToS3d4SdzfUVvM57_mOEL6wONtsOMivJilEOSDRMRKzQRirdRf7RbVpxt0a31-KeIMhSD1p_AfBuHSDI%3D&tracking_referrer=www.zeit.de
http://www.zeit.de/2016/15/oxytocin-hormon-gehirn-forschung/seite-2
http://www.netdoktor.de/medikamente/oxytocin/
https://psylex.de/psychologie-lexikon/oxytocin/oxytocin.html
Ingestion
Ingestion period:
short term: minutes - couple of hours
'Off-label' use: long-term use

Ingestion method:
infusion
nasal spray (mostly 'off-lable' use)
Cardiac arrhythmia
Too slow/fast heartbeat
Raised blood pressure
Headache
Nausea and emesis
Allergic reaction
Continued contraction of the uterus
Side Effects
Not only the 'Love'- hormone
Living in a social envirmonment
Very important for childbirth
Research for medical oxytocin continues
1. Oxytocin
2. Discovery
3. Chemical Messenger
4. Physiological Effect
5. Psychological Effect
6. Oxytocin as Medication
7. Conclusion

Structure
https://de.wikipedia.org/wiki/Oxytocin
https://de.wikipedia.org/wiki/Oxytocin
https://www.hghprescription.com/hormone-replacement-therapy/what-you-need-to-know-about-the-hypothalamus-gland/
https://de.wikipedia.org/wiki/Henry_Hallett_Dale
https://pages.vassar.edu/sensoryecology/prairie-voles/
http://sites.tufts.edu/emotiononthebrain/2014/12/08/the-neuroscience-of-love/
http://birthofanewearth.blogspot.de/2016/08/the-ugly-truth-about-use-of-pitocin.html
Cys
– Tyr – Ile – Gln – Asn –
Cys
– Pro – Leu – Gly (NH2)
S S
Maternal behavior
Bonding
Social recognition
Reduce anxiety
Increases trust
Stress resistance
Distribution of neurotransmitter
Psychological Effect
Full transcript