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Lysosome

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Cameron McPherson

on 23 January 2013

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Transcript of Lysosome

Lysosome Summary / Facts Lysosomes are specialized vesicles which contain digestive enzymes, these enzymes break down foreign materials which may enter the cell.

The name lysosome means “releasing body”.

The word lysosome was derived from two Greek words, 'lysis' which means destruction or dissolution and 'soma' which means 'body'.

Lysosomes were discovered in 1949, by a Belgian cytologist, Christian de Duve.

Lysosomes are usually only found in eukaryotic animal cells. Structure Lysosomes are spherical bag like structures that are bound by a single layer membrane, however, the lysosome shape and size may vary to some extent in different organisms.

These spherical organelles are bound by a phospholipid bilayer and are about 0.2 to 2 μm in diameter.

Lysosomes are actually membranous sacs filled with enzymes. They are found in all eukaryotic cells and act as 'garbage disposal' or the 'digester' of the cell. Location in the Cell Lysosomes float in the cytoplasm

Lysosomes are not visible under a light microscope, it can only be seen with an electron microscope Functions Lysosomes are acidic, with a pH of 4.8. This acidic pH is maintained by pumping protons

Lysosomes contain over 60 different types of powerful digestive enzymes that are used to destroy invading matter and unwanted cellular material

Some examples of enzymes present in the lysosomes include nucleases, proteases, lipases and carbohydrases
Malfunctions Lysosomal malfunction leads to about 50 different types of rare inheritable metabolic disorders. New ones continue to be identified.

Lysosomal storage diseases are characterized by the presence of abnormally enlarged lysosomes containing accumulated undigested cellular components.

The life expectancy of the storage diseases is highly variable and those with severe forms may only survive up to 5-10 years of age. These diseases are currently incurable and the treatments available mostly lessen the symptoms. Work Cited

"cell." lysosomes. N.p., n.d. Web. 20 Jan. 2013. <www.buzzle.com/articles/lysosomes-function.html>.

"illustration of cell structure: lysosome by Russell Kightley Media." Russell Kightley Media: Scientific Illustrator (science illustration, graphics and animation) Home Page.. N.p., n.d. Web. 20 Jan. 2013. <http://www.rkm.com.au/CELL/organelles/lysosome.html>.

"lysosomes." lysosomes. N.p., n.d. Web. 20 Jan. 2013. <hyperphysics.phy-astr.gsu.edu/hbase/biology/lysosome.html>.

MLA formatting by BibMe.org. They break down complex proteins, carbohydrates, lipids and other macromolecules into simpler compounds. These simple compounds are returned to the cytoplasm and are used as new cell building materialsAnother interesting function of the lysosomes is to repair the damage to the plasma membrane. They serve as membrane patch and help in sealing the wound in the plasma membraneLysosomes are also involved in programmed cell death, or autolysis, which is a catabolic process involving degradation of the cell's own components. This is the reason why lysosomes are often known as 'suicide sacs' Functions
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