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Transcript of Osteomalacia
Signs and Symptoms
In the early stages you may not experience any symptoms at all.
As it worsens it is possible for people to begin to feel bone pain and muscle weakness.
You most often feel pain in your lower spine, pelvis, hips, legs and ribs.
decreased muscle tone, weakness in the arms and legs, reduced ability to get around.
Replenishing with Vitamin D: take vitamin D supplements by mouth for several weeks
Also given through an IV
Treating any condition affecting vitamin D metabolism, such as kidney failure or primary biliary cirrhosis, often helps improve the signs and symptoms of osteomalacia.
How it Affects the Skeletal System
Size of the skeletal elements remains the same, but their mineral content decreases, softening the bones.
During osteomalacia osteoblasts have laid down a collagen matrix, but there is a defect in its ability to be mineralized.
Board, A. E. (2012, July 19). Osteomalacia. Retrieved from
Case-Lo, C. (2012, August 7). Osteomalacia. Retrieved from
Holick, M. F. (1997). Osteomalacia and rickets. Retrieved from
Mayo Clinic Staff. (2011, May 3). Osteomalacia. Retrieved from
Explain what Osteomalacia is, and how it effects people.
Identify its key causes and symptoms.
Understand how it affects the skeletal system.
Low calcium levels
Not enough exposure to sunlight
Malabsorption of vitamin D
Kidney Failure and acidosis
Lack of phosphate in diet
Factors that Reduce Vitamin D
Having very little exposure to sunlight
Shorter days of sun
Using very strong sun screen
Osteomalacia is most often diagnosed using a blood test to check for any low levels of calcium, vitamin D or phosphorus in your blood.
Other tests include x-rays, imaging tests and bone biopsies.
With adequate and appropriate treatment to the cause of the calcium and vitamin D deficiency, some people will notice improvement of symptoms within a few weeks.
Full correction of calcium replacement and complete strengthening of bones should result in complete bone healing and repair in approximately six months
Osteomalacia is a bone disease that softens the bones during the bone building process.
It is often confused with osteoporosis because both can lead to bone fractures, but osteoporosis is weakening of pre constructed bone, which means it is not part of the bone building process.
In children, a defect in the mineralization of the osteoid in the long bones and the failure or delay in the mineralization of endochrondal new bone formation at the growth plate leads to the classic skeletal deformities of rickets.
Mineralization defect takes on a different character due to the failure of mineralization of newly formed osteoid at sites of bone turnover of periosteal or endosteal apposition