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The Genetics of Sex

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Jennifer Dever

on 7 February 2017

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Transcript of The Genetics of Sex

The Genetics of Sex
Sex Determination

C. elegans
Sex Determination in Mammals
switch controlled by X:A
X:A = 1, hermaphrodite
Genetic Switch controlled by X:A
X:A = 1,
sxl
ON

Drosophila
X:A = 0.5, sxl OFF
X:A = 0.5, Male
Main Genes Identified Thus Far:
Sry
Sf-1
Wt-1, Wt-4
Dmrt-1
Sox-9
Sox-8
Dax-1
Dhh
Fog2
GATA4
Emx2
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001899
http://dx.doi.org/10.1530/JME-14-0018
Dosage Compensation (dealing with fewer gene products with Y or W)
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