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Transcript of Blood Types
The Rh Factor is an antigen located on the surface of the RBC
If the RBC has the Rh factor, the blood is considered Rh-positive(+)
If the RBC lacks the Rh factor, it is said to be Rh-negative(-)
85% of the population is Rh-positive(+)
Anti-Rh antibodies ARE NOT naturally carried in the plasma.
However in two conditions the plasma of a Rh-negative(-) person can develop anti-Rh antibodies.
What would happen if a person had the B antigen on the RBC and the anti-B antibodies in the plasma?
Accidental administration of Rh-positive(+) blood (donor) to an Rh-negative(-) person(recipient).
The Rh antigen of the donor stimulates the recipient to produce anti-Rh antibodies
Person is said to be sensitized.
What happens if the Rh-negative(-) recipient is given Rh-positive(+) blood a second time around?
Blood Types & Rh Classification System
Antigens& Blood Types
ABO grouping contains four blood types: A, B, AB, and O.
A and B refer to the antigen on the RBC.
Person with type A blood, has the A antigen on the RBC.
Person with type B blood, has the B antigen on the RBC.
Person with type AB blood, has both A & B antigens on the RBC.
Person with type O blood, has neither A or B antigen on the RBC.
Specific antibodies are found in the plasma of each blood type:
Type A blood has anti-B antibodies in the plasma
Type B blood has anti-A antibodies in the plasma
Type AB blood has neither antibodies
Type O blood has both antibodies in the plasma
To avoid giving incompatible blood, the donor is TYPED & CROSS-MATCHED!
The anti-Rh antibodies in the plasma will attack the Rh antigen of the Rh-positive(+) blood
Clotting & hemolysis
The hemolysis causes a rapid rise in plasma levels of bilirubin
Causing severe jaundice and a condition called Kernicterus
Baby is also anemic
Blood is classified according to the specific antigens on the surface of the RBC.
By: Nelly Guerrero