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Epidermodysplasia Verruciformis

Anatomy skin project

Taylor Reilly

on 31 October 2012

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Transcript of Epidermodysplasia Verruciformis

Rachel Bondy, Morgan Bui,
Taylor Reilly, and Becca Wassel Epidermo: outer layer of cells
Dysplasia: abnormality of development

Verruca: wart of any kind Epidermodysplasia verruciformis Inherited disorder
most commonly autosomal recessive
usually begins in infancy or childhood Causes Effects Treatment: No definitive treatment
Preventive measures
Sun avoidance
SCC treatment
minor surgical procedures
larger and more invasive versions may require surgical management and/or radiation therapy
Topical creams once diagnosed
Photodynamic therapy (if anything found)
Autotransplantation of skin Questions: 1) What is the stem meaning "wart of any kind"?

2) Being born with Epidermodysplasia Verruciformis makes you more likely to contract which virus? Epidermodysplasia Verruciformis Kunkel pd.7 (cc) image by nuonsolarteam on Flickr Universal
all races
no sexual preference Epidermodysplasia Verruciformis Defective cell-mediated immunity or association with immunosuppression
Programmed cell death to eliminate those with DNA damage
Failure to do so may result in transformation of squamos epithelium
HIV infection
Organ transplantation
Graft versus host disease: donor's immune system attacks recipient's tissue after transplant
Idiopathic lymphopenia
Abnormally low level of lymphocytes in the blood
Lymphocytes are a white blood cell with important functions in the immune system non-melanoma skin cancer
risk of metastasis
Spread of disease from one organ/part to another organ/part that is non-adjacentbehavior dependent on site of origin flat, wart-like lesions

flat-topped papules with scaly, hyperpigmented or hypopigmented, sometimes confluent patches or plaques

Flat macules and reddish brown plaques with slightly scaly surfaces and irregular borders (may resemble tenia versicolor)

verrucous or seborrheic keratosis –like lesions; commonly seen on sun-exposed skin, including dorsum of hands

lesions may progress to form large plaques and nodules, or they may transform into invasive squamous cell carcinomas, most commonly between the ages of 20 and 40 years. Primary Skin Lesions Squamos Cell Carcinoma http://emedicine.medscape.com/article/1131981-overview
http://www.cdc.gov/hpv/ Bibliography Human Papillomavirus (HPV) (HPV) is the most common sexually transmitted virus in the United States.
At least 50% of sexually active people will have genital HPV at some time in their lives.
Chronic infection with more than 40 types
Full transcript