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Handling Drug Information Request

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dzul azri mohamed noor

on 26 February 2018

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Transcript of Handling Drug Information Request

Handling Drug Information Request
1. What is the two aspects of pharmacoinformatics?
a) Scientific

b) Service
2. Under which pharmacoinformatic aspects does this research falls into?
a) MGMT methylation correlation with temozolomide sensitivity
b) e-prescribing and medication error
List the function of DIS.
1. Provide comprehensive and evaluated information

2. Disseminate information to health professional

3. Disseminate information for general public

4. Collect, analyze and maintain updated info

5. Design, produce and distribute drug info material

6. Give information on poisoning and toxicology
3. What are the activities in DIS?
a) Service & administration

b) Education & training

c) Scholarly activities
4. Name which category of activity these fall into
1. Provide unbiased evaluation in P&T committee
2. Involve in pharmacovigilance studies
1. Reason for documentation

2. Information to be documented

3. Approach to answer query

4. Query analysis

5. Provide response
Importance of documentation
1. As a record of service

2. Quality evaluation

3. Service improvement

4. Other management activities
Information needed
1. Time & Date of request

2. Requester background

3. Question

4. Question background or patient information

5. Query classification

6. Purpose of query
Requestor background
a) Name

b) Address / Ward

c) Phone number

d) Category
Information needed (cont.)
7. Answer given

8. Reference given (if any)

9. Reference used to answer query

10. Name of the person answering query

11. Date and time of answering query

12. Other info eg patient follow-up information
Patient information
1. Patient demographics

2. Current & past medication

3. Relevant medical history

4. Relevant lab result

5. Others
Steps in answering query
1. Obtain requester background
determine the purpose of query

2. Obtain query background
patient information
Classify query

3. Do a systematic search
Type of reference

4. Evaluate information
Summarise answer & give response

5. Follow-up
Why classify query?

a) To identify whether need further information

b) To identify type of reference

c) To determine level of answer
Query classification
1. Drug Identification

2. Drug availability

3. Drug general information

4. Drug formulation

5. Drug dose

6. Side effects or adverse effect

7. Drug interaction

8. Drug compatibility

9. Drug choice or therapeutic efficacy

10. Pharmacokinetic

11. Poisoning or toxicity

12. Disease condition
Type of References
a) Tertiary
Drug Info, Pharmacotherapy

b) Secondary
PubMed, IDIS

c) Primary
Journal, Clinical Trials
Additional information needed for certain query
1) Drug dose
Drug indication
Patient demographic
Organ function
Other concurrent drug
Drug allergy

2) Drug Interaction
Type of drug
Dose for each drug, time and duration of administration
Clinical sign & symptom
Other concurrent drug
3) Poisoning
Patient demographic
Type of drug or suspected item
Amount ingested
Route of Administration
Time taken
Other drug/ingredient taken
Medical illness
Organ function
Sign & Symptom
1) Information must be useful and timely to doctor

2) Systematic search strategy
How to ensure this?
1) Determine when the answer is needed
Search according to time needed
Give priority to critical query

2) Determine scope of information searching
based on query background and classification

3) Start with tertiary reference
get a broader picture first
avoid misunderstanding
tertiary ref usually list down primary ref
choose early ref based on query classification, requester background and query scope
Give response
1. Use reference related to patient context

2. Answer what you have been asked

3. Use suitable terminology

4. Identify if patient has been given advice previously by doctor

5. Inform any limitation to answer

6. Ensure the information is enough

7. Prepare for additional query
Caller : Hello, is this the Drug Information Service Unit?
Pharmacist : Yes it is. My name is Mr Loh. I am the pharmacist in-charge of
the unit. How can I help you?
Caller : I am Dr Rajendran from the Endocrinology Clinic. May I know
what is the maximum dose for Glibenclamide?
Pharmacist : The maximum dose for Glibenclamide is 20 mg/day.
Caller : Thank you.

Give your assessment on the drug information request handling by the above pharmacist. If you are in the same situation, state SIX (6) questions that you would asked in order to give a better response to Dr Rajendran. Give your reason for each one of them.
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