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Immune System Recap

OCR Biology and AQA Human Biology - Workshop

Tre Briercliffe

on 26 November 2013

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Transcript of Immune System Recap

On the white-board: What is an antigen?
eat - cell - break down
constant region
B cell Activation
Specific and Non specific immune response
It's the difference between buying a jacket in Burtons/ Dotty P's compared to getting one made at Saville row
T cell activation
Primary and Secondary Immune Response
Specific immune response: B cells and T cells
Non specific immune response: Phagocytosis
Active: You make the antibodies
An antigen is a molecule that stimulates an immune response
T lymphocytes
Found in Lymph node
Mature in Thymus
Antigen presenting cell to lymph node
Memory helper and killer cells
Killer T cell - bind and kill pathogens
Helper T cells - cytokines
Clonal selection
Binds to T cell with complementary receptor
found in Lymph node
Mature in bone marrow
B lymphocytes
APC binds to antibody and activates B cell
Clonal selection
Plasma cells - secrete antibodies
memory cells - ready for secondary infection
pathogen engulfed
forms phagosome
phagosome and lysosome fuse
digestive enzymes bread down pathogen
waste removed: excytosis
sometimes: Antigen presented on outside
variable region
binding side
Y shaped protein molecule
draw and label and antibody that would bind to the green antigen
amount of antibody
Second infection - more antibodies, quicker response
initial infection: takes time to build up antibodies: why?
Passive: You are injected/ given the antibodies
long lasting
short lived
Artificial: gained by deliberate exposure
Natural: gained in the normal course of living process
Full transcript