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Scientific Etymology Porphyria

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Louise L

on 13 March 2013

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Transcript of Scientific Etymology Porphyria

Porphyria Facts and Fiction Christina L Truth is stranger than fiction, but it is because Fiction is obliged to stick to possibilities; Truth isn't. - Mark Twain What is Porphyria? Acute Porphyria Cutaneous Porphyria Porphyri-ia - a Condition of being purple From the Greek Porphyra A group of eight genetically unique disorders that effect the enzymes of Heme and Porphyrin Porphyr-in - a substance of purple. Any of a group of nitrogen-containing organic compounds that occur in protoplasm and form the basis of animal and plant respiratory pigments Porphyria Cutanea Tarda A subgroup of porphyrias in which the patient develops liver disease and rashes on body parts exposed to the sun Acutus- Latin for Sharp or rapid Sound Familiar? The Madness of King George the III An explanation as to King George the III's erratic behavior probably a form of intermittent Actue Intermittent Porphyria Porphyria in Popular Culture Porphyria's Lover- a poem by Robert Browning of the brutal murder of a woman named Porphyria detailing the effects of physiologically throughout the poem. Who in the poem has Porphyria though? You decide: http://dft.ba/-porphyriaslover Treatment of Porphyria Urine of a person afflicted with Porphyria Normal Urine Cutanea - Cutis Latin for skin
Tarda - Probably from the latin Tardus (adj.) for late Cutaneous Porphyria has similar characteristics to the age old tales of vampires
- Photosenstivity
- Which is accelerated by Garlic (Tizani 136)
-It's possible it was more widespread especiually in small villages Starting in the sixties and re-emerging in the eighties many believed that the similarities between Porphyria could be the link to the horror stories of vampirism. Vampires and Porphyria Symptoms of the Porphyrias Acute Porphyria
- Abdominal Pain, Nausea, Vomiting, Neuropathies, Psychiatric symptons
- Barrage of testing, wait and see approach, family case study Bibliography Most Common Type Photo-senstivity - Photos from greek meaning light neur-o-path-y - a disease of the nerves Further Breakdown of the Porphyrias Porphyria erythropoietica - mild form of porphyria with leisions and excess poryphin in feces and erythrocytes erythr-o-poiet-ica - pertaining to the production of red blood cells erythr-o-cyt-es - red blood cells Porphyria Hepatica - disturbance of liver metabolism often caused by hepatitits, poisoning by heavy metals, and other coniditons hepat-ica - pertaining to the liver All Porphyrias are genetic, however how they are carried differs from Porphyria to Porphyria (autosomnal, somnal, X-linked) and some have been linked to some environmental exposures dextrose infusions, analgesics, and hematin. Constant monitoring of those afflicted with the condition to help remedy other aspects Those with the photosensitivity aspect of the condition must avoid sunlight and there is a drug to help with the effects. hemat-in - a drug pertaining to blood
an-alges-ic - a drug reliving pain Evidence for this is presented as some of his descendents being diagnosed with Porphyrias and description of as well as the well documented erratic behavior which could be a part of the neurological aspect of Porphyria Primarily affect the nervous system In addition due to the low iron amount iron supplements is necessary as well So What is Fact and Fiction? Vampirism has been knocked as a possible explanation since about the 90s due to the rarity of the disease and the variety of folklore on vampires themselves "The Royal Disease" for George the III on historical evidence could, according to WHO, be anything from bipolar that eventually devolved into Alzheimers or dementia. The "Royal Disease" Venes, Donald, and Clarence Wilbur Taber. Taber's Cyclopedic Medical Dictionary. Philadelphia: F.A. Davis, 2005. Print. One of the original articles that first put forth the idea of the Porphyrias being associated with vampirism contains a lot of ifs, ands, and buts that the many have decidedly ignored Cox, A. M. "Porphyria and Vampirism: Another Myth in the Making." Postgraduate Medical Journal 71.841 (1995): 643-44. Ovid SP. 18 Nov. 2009. Web. 25 Feb. 2013. Oversimplifying the Past Siles, Christiaan M., Christopher K. Florkowoski, and Linda S. Pike. "A Right Royal Porphyria Fallacy." Clinical Chemistry 58.3 (2012): n. pag. Print. "The Myth of Vampires and Porphyria." The Myth of Vampires and Porphyria. N.p., n.d. Web. 13 Mar. 2013. http://www.chemicallyspeaking.com/archive/2010/11/01/the-myth-of-vampires-and-porphyria.aspx "It is characterized by excessive excretion of porphyrins, episodes of acute abdominal pain, sensitivity to light, and neurological disturbances. The disorder is sometimes precipitated by the excessive use of sulfonamides, barbiturates, or other drugs." - Tabers Questions? Porphyria cutaneous tarda
- Blistering of the skin
- Liver problems, hepatitis is common among patients
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