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Introduction to One Health

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Dan Diseases

on 25 August 2017

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Transcript of Introduction to One Health

An interdisciplinary approach to the health of people, animals and the environment.
Course overview:
1. Discuss One Health in the context of
- zoonotic disease
- environmental health
- conservation
- whatever you want!

2. Learn some techniques
- conceptual diagrams
- communication by story-telling
- prezi
- building partnerships

3. Write.

4. Embrace uncertainty and humility.
Project - data/science analysis
Writing assignments
Class presentation

See the syllabus for further details (though guaranteed to change)
June 2011

Case investigation…
How did exposure occur?
Will there be more cases?

Gram-negative coccobacillus
Vertebrate reservoir: lagomorphs & rodents
Other exposures: ticks, deer fly, dust etc.
Disease: mild to life-threatening (ulcers, fever, sore throat, diarrhea septicemia, septicemic meningitis, pneumonia)
Bioterror agent
The differences?
White coats
Applied nature

study of the distribution and determinants of health-related states or events in specified (human) populations, and the application of this study to control health problems

study of the distribution of organisms and interactions with each other and their environment
Common ground:
patterns of distribution & abundance of organisms over time and space; attempt to infer or demonstrate underlying processes i.e. causal relationships
Scientists pride themselves on being objective and systematic, but when it's you with an arachnid in your nasal cavity, that sense of distance goes right out of the window. My scientific curiosity won out, but it still took all my willpower not to claw madly at my face.
- Tony Goldberg
Discovering it in my nose had been alarming enough, but thinking about it crawling across my face to get there was truly disturbing.
A biologist can spend a whole career hoping to make such a breakthrough, and there's a special kudos attached to being able to carry out a study on a subject of which you have personal experience. The discomfort and revulsion I went through is a very reasonable trade-off. I feel genuinely grateful to the tick for choosing me as its host.

Syndrome noticed in late 1970s, early 1980s.
By summer of 1984 = 4000 cases worldwide; 600 in San Francisco
Now - known to have caused 30 million deaths.

1986: named as HIV
The Course...
Your favourite journal/science blog etc.
Be proactive...

Course nuts & bolts
What is expected of you?

Ask questions (can cater for introverts and extroverts)
Be pro-active (what interests you?)
Respectful of classmates
San Francisco Bay Area
Interdisciplinary study of health: epidemiology, ecology, diagnostics...

Other reasons to feel nervous?
Sign up...
Contact details:
Tularemia - Francisella tularensis
"Here's what you have to come to understand. That the AIDS pandemic is traceable to a single continent event. That this event involved a bloody interaction between one chimpanzee and one human. That it occurred in southeastern Cameroon, around the year of 1908, give or take. That it lead to the proliferation of one strain of virus, now known as HIV-1 group M. That the virus was probably lethal in chimpanzees before the spillover occurred, and that it was certainly lethal in humans afterward. That from southeastern Cameroon it must have traveled downriver, along the Sangha and then the Congo, to Brazzaville and Leopoldville. That from those entrepots it spread to the world."
David Quammen
Dan Salkeld

What else do we learn from this case?

A smaller world...
Globalization and the spread of disease
One Health concept: a strategy for expanding interdisciplinary collaborations and communications in all aspects of health care for humans, animals, and the environment.

Other terms: Ecohealth, Conservation Medicine

Potential to provide new insights…

(domestic, livestock, wildlife)
Is this 'One Health?'
Is this 'One Health?'
That was 1908...
Hotspots of Emerging Infectious Diseases
So maybe this is 'One Health?'

Is this 'One Health' too?
Animals, humans and environment interact...
Anthropology + ecology + entomology + epidemiology + geography
Highly connected world...
Actually, it used to be 'One World, One Health...'
Room #432; brand new, rather lovely Biology building
Full transcript