Prezi

Present Remotely

Send the link below via email or IM

Copy

Present to your audience

Start remote presentation

  • Invited audience members will follow you as you navigate and present
  • People invited to a presentation do not need a Prezi account
  • This link expires 10 minutes after you close the presentation
  • A maximum of 30 users can follow your presentation
  • Learn more about this feature in the manual

Do you really want to delete this prezi?

Neither you, nor the coeditors you shared it with will be able to recover it again.

DeleteCancel

Make your likes visible on Facebook?

Connect your Facebook account to Prezi and let your likes appear on your timeline.
You can change this under Settings & Account at any time.

No, thanks

Neurolupus: Correlation MRI-Pathology

No description
by Florian Stierlin on 15 April 2011

Comments (0)

Please log in to add your comment.

Report abuse

Transcript of Neurolupus: Correlation MRI-Pathology

Presentation PLAN Introduction
SLE
Neurolupus
Antiphospholipids syndrome
Objectives
Material and Methods
Description of patients
Description of the tissue
Description of the 7-Tesla MRI
Description of the immunochemistry
Results
Conclusion and discussion INTRODUCTION A multisystem autoimmune disease characterized by a vast array of auto-antibodies (mostly Anti-nuclear antibodies (ANA))
Etiology = still unknown
Pathogenesis = (Hypothesis stage) Failure of self-tolerance leading to continuous formation of auto-antibodies
Diagnosis = SOAP BRAIN MD
Systemic Lupus Erythematosus NEUROLUPUS - Neurolupus is defined as a SLE with neuropsychiatric involvements
- Up to 50% of SLE patients may have brain involvement
- Main lesions
Microinfarcts
Vasculopathy (vasculitis = rare!)
- Clinical manifestations
Central nervous system involvement (aspetic meningitis, headache, chorea, seizure disorder, anxiety and mood disorders, psychosis...)
Peripheral nervous system involvement may also occur
- Diagnosis
Prove SLE
Confirme the presence of some neuropsychiatric manifestations
Some investigations are recommended but no real gold-standard
The diagnosis is more made as an "exclusion diagnosis"
See the full transcript